Anti-oxidant and anti-cancerous properties of lantana camara against mcf-7- in vitro
DOI:
https://doi.org/10.70066/jahm.v12i2.1277Keywords:
Keywords: Lantana camara, MCF-7, cancer, Antioxidant, PhytochemicalAbstract
ABSTRACT:
Background: Globally, breast cancer is thought to be the primary cause of cancer-related mortality. Many medical preparations, such as those used in Ayurveda and homoeopathy, are recommended in our traditional systems of medicine to address a variety of human health conditions. Plants with antioxidant properties are a great source for discovering anticancer medications against breast cancer. Objective: The purpose of the current study was to examine the anti-cancer and antioxidant properties of an etanolic extract of Lantana camara (LC) leaves against MCF-7. Materials and Methods: Total phenolic content of the extract was determined by using folin-ciocalteu reagent. The DPPH and H2O2 assay were used to measure the free radical scavenging activity of the LC plant extract. The MTT assay was used to evaluate the cytotoxic efficacy of ethanolic extract of the plant against MCF-7 at various concentrations. Results: Based on the result it was found the presence of phenolic content in ethanolic extract of LC leaves. Conclusion: According to the current study, LC leaf extract significantly possesses antioxidant and anti-cancer properties against breast cancer cell line. This effect may be attributed to the extract's ability to scavenge free radicals.
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