STUDY ON CLINICAL EFFICACY OF SANJIVANI VATI & LASHUNADI VATI IN MANAGEMENT OF DIARRHEA PREDOMINANT IBS: A PILOT STUDY
DOI:
https://doi.org/10.70066/jahm.v2i6.188Keywords:
Sanjivani vati, Lashunadi vati, Diarrhea predominant IBSAbstract
Background: Irritable bowel syndrome (IBS) is a functional bowel disorder in which abdominal pain is associated with
defecation or a change in bowel habit. IBS commonly causes cramping, abdominal pain, bloating associated with changes
in bowel habits in the absence of any structural abnormality. Depending on the kind of discomfort and bowel habits, IBS
can be sub classified into diarrhea-predominant (IBS-D), constipation-predominant (IBS-C) and IBS with alternate
constipation and diarrhea (IBS-A). Aims: The present study was conducted to evaluate the efficacy of Sanjivani vati and
Lashunadi vati in the management of diarrhea predominant irritable bowel syndrome (IBS-D). Study Design: The study
was a single arm, open clinical trial. Methods and Material: 40 patients of IBS-D attending the OPD of All India Institute
of Ayurveda, New Delhi were selected for the study. All patients were screened on the basis of Rome III criteria of IBS
and were administered with a combination of Sanjivani vati (125 mg twice a day orally after principal meals) and
Lashunadi vati (500 mg twice a day orally after principal meals) for 60 days. Scoring scale based on classical clinical
features of IBS-D was adopted for the assessment of the disease. Statistical analysis used: Wilcoxon’s signed rank test
was applied using spss software to analyze the data. Results: After 60 days of treatment, improvement in clinical features
like abnormal stool form, frequent bowel movements, abdominal pain, abdominal bloating, mucus in the stool, feeling of
incomplete evacuation was found to be statistical significant (p ≤ 0.05). No adverse event was observed during the
administration of trial drugs. Post treatment follow-up was done after one month. No any recurrence of symptoms was
reported. Conclusions: The combination of Sanjivani vati with Lashunadi vati is found to be effective in managing
diarrhea predominant irritable bowel syndrome.
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