Journal of Ayurveda and Holistic Medicine (JAHM)

Guillain–barre syndrome (GBS) rise in complications due to diagnostic pitfalls: A case report

2025-03-30T17:32:43+0530

Guillain-Barre syndrome (GBS) is an abrupt, complex degenerative neurological condition that can manifest as either acute or chronic. It has been observed that antecedent infections serve as significant risk factors for acquiring GBS, in current case study we observed the antecedent infection of Chikungunya virus and recent history of Covid 19 vaccination. Although the aetiology is yet unknown, the pathophysiology demonstrates demyelination of the spinal nerve roots, which is marked by muscle stiffness and symmetrical limb paralysis.In cases of severity, early diagnosis and immediate treatment are crucial. Here we discuss the case of GBS with complications due to diagnostic pitfalls. This case study focuses on 60 years old male patient exhibiting the complaints of paraesthesia in lower limb and increasing muscle weakness.In this case firstlythe patient was misdiagnosed with appearance of small hypodensity in left caudate nucleus in CT scan study of brain. After one week patient’s conditions was getting worseand shifted to another hospital for further diagnosis and treatment. After thatin radiological examination of brain (CT scan) atrophic alterations were seen.Cerebrospinal fluid analysis and Nerve Conduction Velocity study showed demyelinating polyradiculoneuropathy like AIDP type of GBS.In this case study patient was treated with intravenous immunoglobulin (IVIG) transfusion for 5 days and progress of slight movements of limbs was observed.The significance of precise diagnosis and prompt implementation of suitable treatment approaches in the management of GBS is highlighted by this case study.

The Impact of Yoga Practices on Inflammatory Markers: A Scoping Review

2025-03-22T12:23:38+0530

BACKGROUND

Most of the life style disorders involving humans in their adult life is characterized by persistence underlying low-grade inflammation. The inflammation adds further insults to the pathogenic damage caused by the disorder. This inflammation is often ignored because it does not produce noticeable effect on the body to draw immediate attention. Yoga has been studied to have an effect on the well-being of the individual. A scoping review had been decided to explore the overall impact of yoga on inflammation by summarizing the existing research. The review focussed on identifying relevant studies that investigate how yoga encompassing practices like asana, pranayama, and meditation, influences inflammation. By examining various study designs and outcomes related to inflammatory markers, the review seeks to provide a broad overview of the current understanding and potential benefits of yoga in managing inflammatory conditions.

METHODOLOGY

A thorough literature search was conducted in PubMed, Embase, and Cochrane up to April 2024 to identify studies examining the impact of yoga on inflammation. The search utilized keywords associated with yoga and inflammation, and was restricted to studies published in English.

RESULTS

We had identified 66 studies involving 3,774 participants across multiple countries. Participants included healthy adults as well as individuals with conditions such as heart failure, cancer, autoimmune disorders, respiratory diseases, neurological disorders, and others. The collective scientific evidence from these diverse studies indicated that yoga practices showed promising effect in reducing inflammation across different populations and health conditions.

CONCLUSION

The review indicated that yogic practices potentially reduced inflammation, although the study designs varied considerably. While many studies reported positive impacts on inflammatory markers, some did not observe significant changes. To confidently recommend yoga as a primary therapy for inflammation, additional well-designed, randomized controlled trials with sufficient statistical power and a broader scope of inflammatory parameters are necessary.

A Historic milestone – JAHM is now indexed in SCOPUS!

2025-04-20T13:15:07+0530

The Journal of Ayurvedic and Holistic Medicine has reached an important milestone in its history. We are extremely grateful and pleased to tell you that it is officially indexed in Scopus, one of the most esteemed abstract and cited databases for the world's peer review literature. This perception is more than just praise. It is evidence of the tenacity, commitment and academic integrity of our vibrant academic community. It demonstrates that our goal of promoting areas of improved research and innovation in Ayurveda and holistic health is recognized worldwide.

Effect of shigru (Moringa oleifera Linn.) patra choorna tablet in the management of subclinical hypothyroidism- A single arm open labeled clinical trial

2025-04-07T13:39:42+0530

Background: Due to increasing global incidence of Thyroid disorders and their effect on day today life, numerous studies are being conducted to identify potential treatment for Anukta vyadhis. So many drugs have been known for Thyroid controlling properties; but researches regarding its clinical efficacy are less. Objectives: The purpose of this study was to evaluate the effectiveness of Shigru (Moringa oleifera Linn.) Patra churna tablet in the management of Subclinical Hypothyroidism. Materials & Methods: In this single arm open labeled clinical trial , all eligible participants were assigned to receive the intervention without randomization. Patients visiting Specialty OPD of KLE Ayurveda Hospital, Belgavi with signs & symptoms of Subclinical hypothyroidism like weight gain, hair-fall, edema, irregular menstrual cycle and 30 patients of 20 to 60 years age group of either sex without any history of Thyroid related disease, Diabetes Mellitus or Hypertension were included; TSH value above normal range but below 10 IU/L. Shigru patra churna tablet was given 1 gm twice a day before food for period of 42 days. The assessment of changes observed in Thyroid profile as well as in Anthropometrical changes like waist circumference and weight loss and clinical symptoms like Keshapatana (Hairfall), Medovriddhi(gradual weight loss), Shotha (Facial or generalized edema), Aniyamita artava (Menstrual disturbance), Klama (Lethargy or easy fatigue) was carried out. Results: After 42 days of intervention, Thyroid profile, especially TSH and other parameters were significantly decreased when compared with baseline. No adverse drug reaction was reported during and after the intervention with the use of study drug. Conclusion: Shigru patra churna was effective in the management of subclinical hypothyroidism and free from any adverse effect on patients.

Exploring the link between Grahanidosha, and Chronic Neck and Back Pain: A Cross-Sectional Study

2025-03-30T22:53:38+0530

Introduction: Chronic back pain is a significant public health issue, often leading to work absenteeism. Traditional treatments may not fully address the root causes, particularly the role of gut health in chronic pain. This study explores the association between grahaṇīdōṣaḥ, a digestive dysfunction concept in Ayurveda, and chronic neck and back pain.

Methodology: A cross-sectional analysis was conducted at VPSV Ayurveda College Hospital involving 164 patients with chronic neck and back pain. The study used a newly validated assessment tool to identify grahaṇīdōṣaḥ, examining its prevalence and association with pain. Inclusion criteria were patients aged 20-45 with pain persisting for over three months, excluding those with traumatic, infective, or malignant causes.

Results: The study revealed a significant association between grahaṇīdōṣaḥ and chronic pain. Notably, 109 out of 164 patients exhibited features of grahaṇīdōṣaḥ. Statistical analysis showed a strong correlation between digestive dysfunctions and pain sites, particularly low back pain and cervical pain with gastrointestinal symptoms like indigestion and constipation.

Discussion: The findings suggest that underlying digestive issues, as conceptualized in Ayurveda, play a crucial role in chronic neck and back pain. Addressing grahaṇīdōṣaḥ could lead to more effective and holistic pain management strategies, integrating both Ayurvedic and modern medical approaches.

Conclusion: This study underscores the potential association between grahaṇīdōṣaḥ and chronic pain pathologies. Further research should explore the clinical efficacy of integrating these traditional Ayurvedic concepts with conventional treatments to develop a comprehensive approach to pain management.

Scientific Review of Bala Chaturbhadra Churna in Pediatric Practice

2025-04-02T16:36:06+0530

Introduction: Balchaturbhadra churna (BC) is a poly-herbal formulation specifically mentioned in multiple pediatric illnesses especially fever, diarrhea,vomiting and cough. The contents include equal proportions of rhizome of Cyperus rotundus Linn. (Cyperaceae), fruit of Piper longum Linn. (Piperaceae), root of Aconitum heterophyllum Wall. ex. Royale. (Ranunculaceae) and gall of Pistacia integerrima Stew. Ex. Brandis. (Anacardiaceae). Aim and objective: To study therapeutic potentials, safety and efficacy of BC in the light of recent research updates. Material and Methods: A systematic search on bala chaturbadra churna in Ayurveda classics and scientific publications were analysed. Discussion: Over all BC predominantly Katu–Tikta Rasa (pungent and bitter taste), katu vipaka (Bio‑transformed Rasa), ushna veerya (hot potency), Guna (properties) like Laghu (light for digestion), ruksha and properties like Deepana (digestant), Pachana (carminative)and grahi (absorptive). Thus it can cure Ama (metabolic moiety), jwara (febrile illness), trishna (thirst), atisara (diarrhea), kasa (cough) and shvasa (Dyspnea). It did not show any toxic effect in in vitro study. Most of the contents of BC researched to have anti-diarrheal, anti-pyretic, anti-inflammatory, analgesic, immuno-modulatory, anti-asthmatic activity, anti-microbial activity, antioxidant activity, hepatoprotective action and cardioprotective activity. Conclusion: Balchaturbhadra churna is convincingly safe and potent compound formulation for management of pediatric illnesses.

Nigella sativa: A Comprehensive Review on Its History, Traditional Uses, Adulteration, Allied Species, Phytochemistry, and Applications in Cosmetics.

2025-04-01T12:24:30+0530

For centuries, black cumin, also known as Nigella sativa, a flowering plant of the Ranunculaceae family, has been used medicinally. An overview of Nigella sativa's pharmacological, botanical, phytochemical, and therapeutic applications is given in this comprehensive review. It is grown primarily as a rabi crop; its seeds are sown during the cold months and harvested in the spring. Harvest the seeds when the pod is slightly green to preserve the aromatic oil. Pharmacological effects. These incorporate antioxidant, anti-inflammatory, anti-inflammatory, anti-diabetic and anti-cancer properties. In cosmetics, N. sativa is used for its beneficial effects on the skin and hair. These oils and extracts have been formulated in various ways for their antioxidant, anti-inflammatory, and anti-inflammatory properties. Home remedies that use alfalfa include face masks, hair masks, and toothpastes that utilize its nourishing and rejuvenating properties. When used for a long time. The commercially available formulation is N. sativa includes supplements, oils, and personal care products designed to harness its healing abilities. Its rich phytochemical composition and diverse pharmacological activities make it a good candidate for the development of new drugs and cosmetics.

Ayurvedic Insights into Personalized Medicine: A Holistic Approach

2025-04-01T16:17:27+0530

In Ayurveda, individualized medicine is a common practice although it is new to modern medicine. Ayurvedic science illustrates how two individuals with the same disease might just be treated with different Ayurvedic medications. A single disease can also be treated with customized Ayurvedic medications as it develops and evolves inside a single person. Individualized healthcare is the upcoming approach to providing medical treatment that is tailored to an individual's unique genetic makeup, epigenetic patterns, and clinical data. This enables a clear understanding of their distinct genomic profile and ensures uncompromising medical care. PM (personalized medicine) is a treatment based on the genomic profile of the patients that can influence the response to the drug. One of the strategies in the field of healthcare management PM allows a doctor to choose a medicine based on a patient's genetic profile, avoiding negative side effects and increasing the likelihood of successful treatment. In addition, this will be a more affordable method of treating diseases than the current "trial-and-error" method currently in use.

A Philosophical and Scientific Exploration of the Five Sheaths (Pancha Kosha) that Unveiling Consciousness (Chaitanya)

2025-04-03T16:33:09+0530

Background: Consciousness (Chaitanya) has played a significant role in Indian philosophy and modern neuroscience. The Taittiriya Upanishad relies on Pancha Kosha (the Five Sheaths) to explain human existence from the physical plane to the transcendental realm. Western neuroscience uses cognitive and neurological frameworks to study Consciousness, but Vedantic philosophy links these sheaths to realizing the Self (Atman). Objectives: This research focuses on investigating Pancha Kosha's philosophical and scientific facets while looking at their significance in consciousness studies. To give a comprehensive knowledge of mind-body connections by fusing contemporary neuroscience with Vedantic ideas. Methods: The review focused on Vedantic texts, neuroscience, and consciousness research, and a thorough literature analysis was carried out utilizing Cochrane through the PubMed database of Science, Embase, Google Scholar, and institutional archives to explore links between Pancha Kosha, Sharira Traya, and Consciousness. Findings and Discussion: The study emphasizes how the five sheaths interact with awareness. Neuroscience supports Vedantic ideas by showing connections between the Pancha Kosha framework and cognitive processes. The study bridges the gap between philosophy and science by combining spiritual insights with factual facts. Conclusion: The Pancha Kosha concept integrates transcendental and material awareness to offer a comprehensive approach to Consciousness. This work advances modern neuroscience by incorporating ancient wisdom into consciousness research.