Journal of Ayurveda and Holistic Medicine (JAHM)

Critical Manuscript Study of Gutikayogachintamani with Special Reference to its Unique Formulation

Hemangi Mulchandani — 2026-05-24

Background- Manuscripts literally means “Written by hand” which carried the personal touch and clinical understanding of scholars from past centuries. These Manuscript contain centuries of verifiable observations, unique therapeutic formulations, and surgical importance that remain largely unpublished. Despite their Standard and clinical significance, a vast majority of Ayurvedic manuscripts remain unedited and inaccessible to the modern scientific community. Due to environmental degradation, physical negligence and the lack of systematic digitization, this primary source of traditional medicine is at risk of permanent loss, creating a critical gap in our medical system. Gutikayogachintamani is untouched Manuscript present in Oriental Institute of Baroda. This is a truly unique manuscript. After searching other several manuscript centers, we discovered that this is the only surviving copy of the work in existence. The Gutikayogachintamani might have been a specialized manual used by a specific group of Vaidya in a particular region. It is a single folded sheet with 2 folios. Aim & objectives: To Systematically study and translate the manuscript ‘’Gutikayogachintamani’’ and evaluate its therapeutic significance in the context of classical Ayurvedic literature. Methodology- Unpublished and complete Manuscript Gutikayogachintamani is collected from oriental institute of Baroda. Observation: In this Manuscript Two kalpas are given out of which first one is Gutikayogachintamani and other one is Hemagarbhapottaliras. In these Dravya of Formulation with Matra, Preparation method, Indications, Benefits and Aushadhsevankala have been mentioned in detail. Conclusion- This Manuscript includes Gutikayogachintamani, Dravya of Formulation with Matra, Preparation method, Indications and benefits. It is a collection of Two Kalpas. Formulations like Gutikayogachintamani and other should be further studied and clinically explored to see its efficacy. This manuscript represents an invaluable repository of traditional medical knowledge that warrants rigorous scholarly exploration to inform future clinical research and therapeutic practice.

Evaluation of hepatoprotective activity of Murvadi Agada - A polyherbal formulation in Methotrexate induced hepatotoxicity in Wistar albino rats.

Sachin Mangattu — 2026-05-24

Background– In India, drug induced liver injury constitutes most cases of acute liver failure with fatality up to 50%. Murvadi Agada is a classical ayurvedic formulation indicated for the treatment of Gara Visha (concomitant poison); however, its hepatoprotective potential has not yet been scientifically evaluated. Objective- To evaluate the hepatoprotective effect of Murvadi Agada against Methotrexate induced hepatotoxicity using Wistar albino rats. Methods- Thirty Wistar albino rats of either sex were randomly divided into five groups (n=6). Group I served as normal control. Group II received single intraperitoneal injection of Methotrexate 20mg/kg and served as toxic control. Group III and IV were administered with Murvadi Agada (1080 and 2160 mg/kg) orally, respectively, followed by single intraperitoneal injection of Methotrexate. Group V received Silymarin (100 mg/kg orally) + Methotrexate. Silymarin and Murvadi Agada were administered for 7 and 14 consecutive days respectively. On the last day, single dose of Methotrexate was given one hour after drug administration. Results- Methotrexate significantly increased serum AST, ALP, IL-1β (p < 0.01), GGT (p < 0.05) compared to normal control group. Murvadi Agada 1080 mg/kg significantly decreased serum ALT (p < 0.001), ALP (p < 0.01), AST (p < 0.05); Murvadi Agada 2160 mg/kg significantly decreased serum ALT, GLDH (p < 0.001), AST, ALP (p < 0.01), GGT, IL-1β (p < 0.05) and Silymarin significantly decreased serum IL-1β (p < 0.01), AST, GLDH (p < 0.05) compared to Methotrexate group. Single dose of Methotrexate caused areas of focal necrosis in liver sections; Murvadi Agada administration caused dose dependent reduction of inflammatory infiltrate in both groups and no histological changes were observed in Silymarin group. Conclusion– Murvadi Agada demonstrated significant hepatoprotective activity against Methotrexate induced hepatotoxicity. Both doses significantly reduced liver enzymes, with the double therapeutic equivalent dose attenuating GGT, GLDH, IL-1β and histopathology protection.

Biosynthesis of Nd₂O₃, or Neodymium(III) Oxide Nanoparticles with Clerodendrum phlomidis and their antidiabetes and anti-cancer activity: An invitro study

Ayesha Nashita — 2026-05-24

Background: Green nanotechnology involves the utilization of phytochemicals as natural reducing and stabilizing agents that offer an alternative to the traditional synthesis of nanoparticles, which can be considered sustainable. Clerodendrum phlomidis leaf extract is abundant in flavonoids, phenolics, and tannins was used to biosynthesis neodymium oxide (Nd₂O₃) nanoparticles in this work. Materials and methods: The synthesized Nd₂O₃ nanoparticles were characterized by UV -Vis spectroscopy, Fourier-transform infrared (FT-IR) spectroscopy, X-ray Diffraction (XRD) and Field emission scanning electron microscopy (FE-SEM) confirmed the functional groups, crystal structure, and aggregated nano-granular morphology. The antioxidant activity properties were evaluated by 2,2-diphenyl-1-picrylhydrazl (DPPH) and nitric oxide (NO) assays. The anti-proliferative effect of Nd₂O₃ nanoparticles synthesized using C. phlomidis on A549 cells was quantified by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Results: FT-IR showed significant O-H, C=O, C-N, and N-O bands, which are the indicators of phytochemical capping, the examination of the UV-Vis showed that there was a large absorption peak at 425 nm. XRD patterns confirmed the formation of cubic-phase Nd₂O₃ that was crystalline. SEM images showed agglomerated porous structures consisting of small nanoparticles. Nd₂O₃ nanoparticles exhibited significant activity in DPPH assay and NO assay exhibited radical scavenging at 86.71% and 89.56% at higher concentration (100 µg/mL) respectively. The α-amylase and α glucosidase demonstrated 80.54% and 80.52% at higher concentration of 320 µg/mL. At 200 µg/mL, MTT assay revealed a 33% reduction in A549 cell viability. Conclusion: Nd₂O₃nanoparticles synthesized using C. phlomidis demonstrated significant in-vitro antidiabetic, antioxidant properties and cytotoxic activities. It creates environmentally friendly multifunctional nanoparticle-based therapies for the treatment of metabolic and inflammatory diseases.

Significance of Ayurvedic Shodhana Therapy in the Management of Palmoplantar Psoriasis (Vipadika): A Case Report

Simran Garg — 2026-05-24

Background: Palmoplantar psoriasis is a chronic, non-contagious, inflammatory skin disorder that primarily affects the palms and soles. Despite advances in biologic therapies, its management remains challenging. The condition leads to considerable discomfort and disability, limiting a patient’s ability to perform daily tasks and occupational duties. Owing to its complex, multifactorial etiology, effective management usually requires a comprehensive, multimodal treatment strategy. In Ayurveda, its clinical presentation closely resembles Vipadika, a condition marked by Paani-Paada Sphutana (cracking of the palms and soles) accompanied by Teevra Vedana (severe pain). Findings: A 6-year-old boy presented with a 1-year history of patchy, dry, scaly, itchy, and bleeding lesions on bilateral palms and soles, diagnosed as Palmoplantar Psoriasis, and was successfully managed with Ayurveda. Intervention: Shamana Chikitsa (Pacification therapy) according to the Avastha (clinical presentation) of the patient for 11 months, followed by Shodhana (Bio purification), that is Vamana (Therapeutic emesis). Results: The patient reported significant improvement in complaints and Palmoplantar Psoriasis Global Assessment (PPPGA) score reduction from 4 to 1 after Shodhana (Bio-purification). The Dermatology Life Quality Index (DLQI) score improved from 25 to 2. Conclusion: Shamana (Pacification), along with Shodhana (Bio-purification), proved to give more efficient results in terms of reduced interventional duration, rather than Shamana alone in this case. Treatment was well tolerated, and no adverse drug reaction was reported during the entire course. Ayurveda showed great results in clearing the lesions without any complications and without the use of topical or systemic steroids during the whole course of treatment.

Ayurvedic Management of Idiopathic Full-Thickness Macular Hole with Anatomical Closure on OCT: A Case Report

Nelliakkattu Narayanan — 2026-05-24

Background: Macular hole (MH) is a vitreoretinal disease characterized by a full-thickness neurosensory retinal defect in the center of the macula. Although there is no direct correlation, based on the symptomatic presentation of the patient, full thickness Macular Hole (FTMH) can be correlated to Vataja Kaca. Case Presentation: A 61-year-old male presented with a four-month history of blurred vision in the right eye (RE), especially with difficulty in reading small letters, with central scotoma (blurry spot in the center of the visual field), with no marked distortion of lines. Optical Coherence Tomography (OCT) confirmed the diagnosis of FTMH. Intervention: The patient underwent a structured Ayurvedic treatment protocol, focusing on Ama pachana, Samana (palliative), Snehana (unctuous therapy), Brmhana (nourishing), and Vatahara line of treatment. Outcome: After five months, the patient reported progressive improvement in visual clarity of the RE with the absence of central scotoma. Visual acuity improved to 6/9 (logMAR 0.176) in the RE from baseline 6/24 (logMAR 0.602), while near vision in RE improved to N12 from baseline N24 and OCT shows complete closure of the hole. Conclusion: This case highlights the potential efficacy of Ayurvedic therapies in the management of a FTMH, necessitating further larger-scale trials and research in this field for validation.

Ayurvedic Management of Lamellar Macular Hole: A Case Report

Narayanan Nelliakkattu — 2026-05-24

Background Lamellar Macular Hole (LMH) is a retinal disorder affecting partial-thickness in the macula characterized by an irregular foveal contour. Ayurveda correlates LMH to Dwitiya Patalagata Timira, a disorder where vitiated Vata dosha enters the Dwitiya patala (second layer of eyeball), resulting in scotoma, floaters and flashes. Case Description: A 60-year-old male presented with central scotoma, distortion, floaters, and photopsia in the left eye (LE). Unaided Distant Visual acuity (DVA) was LogMAR 0.477, and Optical Coherence Tomography (OCT) confirmed Vitreomacular Traction (VMT) with LMH in LE. Intervention: The patient received one course of Inpatient The protocol included external treatments and internal medications aiming at Shodhana (cleansing) and Samana (pacification). The patient under went one IP and two follow-ups over 12-months. Outcome: The DVA improved 0.477→0.176 LogMAR, and the symptoms of central scotoma, distortion, floaters and flashes reduced considerably. The OCT showed complete closure of LMH with normal foveal contour. Conclusion: This case report shows the effect of Ayurvedic interventions in LMH in maintaining normal contour in the fovea.

Ayurvedic Management of Eosinophilic Esophagitis (Amashayagatavata) -A case report

Rohan Mohandas — 2026-05-24

Background: Eosinophilic Esophagitis (EoE) is a chronic immune-mediated esophageal disorder, often resistant to available standard therapies such as corticosteroids. A condition where a type of white blood cell (eosinophil) builds up in the esophagus, causing inflammation, tissue damage, and dysfunction. It causes chronic swallowing difficulties, food impaction, and pain, often requiring dietary changes, medication, or endoscopic dilation to manage. Clinical Findings: A 23year old male patient visited to hospital presented with complaints of dysphagia, epigastric burning vomiting sensation and burping continued since last four years. Intervention: Under Ayurvedic assessment, this case was taken under spectrum of Amashayagatavata, and a combined protocol of Panchakarma therapy and internal medication was administered. The patient underwent an 8-day yogabasti regimen comprising Niruhabasti with Yashtimadhu Ksheerpaka and a polyherbal kalka including Guduchi, Manjishtha, and Shatapushpa, and Matra basti with Dadimadi Ghrita. Oral medicines included Dhanwantaram Vati, Kamdudha with Mukta, Anuloma DS, and Vomitab syrup. Outcome: USG after two months was normal; endoscopy revealed resolution of eosinophilic inflammation and sliding hiatus hernia. Eosinophil count dropped from 986 cells/cmm to 330 cells/cmm. Symptom resolution was documented via Patient Relief Scale, endoscopic reassessment, and a Quality of Life (QOL) scale. Conclusion: The case illustrates a promising comprehensive approach with yoga niruha basti pattern along shaman yogas for chronic Eosinophilic esophagitis with a seven days IPD and four months follow ups period without any adverse effect reported during treatment with Ayurveda showed patient improvement warranting larger controlled studies.

Integrated management of Medoja granthi (Hidradenoma papilliferum): A rare case report

Aniket Ughade — 2026-05-24

Background - Hidradenoma papilliferum (HP) is a rare benign and adnexal neoplasm, affecting middle aged women. It typically presents as a slow-growing, well circumscribed nodular lesion, in the vulvar or perianal region. Owing to its rarity, and close clinical resemblance to common benign perianal lesions, preoperative diagnosis is often challenging and definitive diagnosis relies on histopathological examination. In Ayurveda, this clinical condition is correlated with Medoja granthi (Benign soft tissue tumor). Clinical findings: A 60-year female came with painless, slow progressive perianal swelling along with discomfort while sitting and occasional serous discharge for 6 months. Perineal ultrasonography suspected the condition as proliferating trichilemmal cyst. The specimen was sent for histopathological study to confirm the diagnosis. Intervention: An integrated approach i.e., antibiotics, analgesics, Chedan Karma (surgical excision) and wound management was adopted. Outcome: The histopathological study confirms the condition as HP. Good surgical outcome was obtained with the integrated approach in the form of complete wound healing and no recurrence. Conclusion: The postoperative outcome in the present case of HP with the chronicity of 6 months was satisfactory, with good wound healing and no evidence of recurrence during follow-up period of 40 days. This case highlights the importance of histopathological examination in diagnosing atypical perianal lesions and demonstrates that an integrative management can yield favorable clinical outcomes in HP. Further research in the integrative medicine is necessary for generating evidence-based results.

Pharmaceutical and Analytical Standardization of Ajamoda Arka with Yavakshara Through Physicochemical Evaluation, HPTLC Profiling, GC–MS Characterization, and Safety Assessment

Tale Vaibhav Vitthalrao — 2026-05-24

Background:
Digestive disorders such as Vataja Udarashoola (abdominal colic) are commonly encountered in pediatric clinical practice. In Ayurveda, these conditions are attributed to Agnimandya, Ama accumulation and vitiation of Vata–Kapha Dosha, resulting in impaired digestion and abdominal discomfort. Classical Ayurvedic formulations such as Ajamoda Arka and Yavakshara are indicated in the management of the above conditions owing to their Deepana, Pachana and Vatanulomana properties.

Objective:

The objective of this work is to analytically standardize Ajamoda Arka with Yavakshara by testing its organoleptic, physicochemical, chromatographic, microbial properties, Heavy metal and Pesticides following standard guidelines.

Materials and Methods:

The preparation of Ajamoda Arka is done according to “Arka Kalpana” given in AFI. Yavakshara prepared using AFI guidelines is mixed with distilled Ajamoda Arka in a specific ratio. “Organoleptic characters”, “clarity”, “pH”, “specific gravity”, “refractive index”, “viscosity”, “volatile matter”, “total acidity”, HPTLC, GCMS, “Heavy metals”, “Pesticides” were done using API guidelines.

Results:
Ajamoda Arka with Yavakshara was clear, colourless and aromatic with salty taste. Physicochemical parameters showed pH 6.34, specific gravity 0.9710, refractive index 1.32507 and viscosity 1.01, indicating stability of the formulation. Volatile matter was 0.13%. Microbial analysis revealed absence of bacterial and fungal growth, confirming microbiological safety within permissible limits. HPTLC analysis reported characteristic bands analogous to α-phellandrene and β-pinene. GC–MS chromatogram revealed several constituents including 9-Octadecenoic acid derivatives, ‘cis-9-Hexadecenal, terpen’ and ‘glycidyl palmitate’, indicating the presence of anti-inflammatory bioactive compounds. Heavy metals were within permissible limits and all tested pesticides were negative, confirming the safety of the formulation.

Conclusion:
The present study establishes preliminary analytical standards and chromatographic fingerprints for Ajamoda Arka with Yavakshara. The results of this pharmaceutical study can serve as criteria for ‘quality control’ and ‘standardization parameter’ for future research. However, further studies can be enriched with safety and stability evaluation for shelf life.

Pharmaceutical and Analytical study of Yashtimadhu Anjana prepared with various wick materials using FTIR And XRD.

Koushik Gumdal — 2026-05-24

Background: Conversion of herbal drugs in soot/carbon can be done and brought in therapeutic practice. Based on this innovative concept, Yashtimadhu Anjana was prepared with 3 different techniques. Aim: Pharmaceutical and analytical characterisation of end product studied for concluding suitable material for soot preparation. Objective: To evaluate pharmaceutical and analytical characterization of 3 different methods of preparation of Yashtimadhu Anjana and conclude the suitable material for soot preparation Material and Methods: For soot preparation 3 substrates were used viz. cotton cloth, surgical cotton and surgical gauze. Precise weighing was done for unbleached standardized cotton cloth (20 cm²). After that, identical masses of surgical gauze and surgical cotton wick were made for comparison. All 3 wicks soaked with GG (Glycyrrhiza glabra) decoction and dried for 7 times & burnt in cow ghee to create black soot. Obtained product subjected for pharmaceutical and analytical analysis according to the Ayurvedic Pharmacopoeia of India. Results: Soot obtained from cotton cloth 10.23gms, surgical cotton 12.89gms and surgical gauze 9.18gms. FT-IR of cotton cloth showed minor specific bands which may be due to environmental exposure or surface impurities. Surgical cotton soot showed minor chemical modifications which may occurred during processing. Whereas surgical gauze does not show any distinct peaks and closely resembles that of purified cellulose. XRD analysis verified, all soot samples were primarily amorphous carbon. Conclusion: Though cotton cloth and surgical cotton produced more soot however surgical gauze may be appropriate for therapeutic purposes. Despite lower yield, surgical gauze may be determined to be suitable substrate because of relatively cleaner spectral profile as per FTIR findings, and all three soot are basically amorphous in nature which was confirmed by XRD analysis.

Ethnobotanical, phytochemical and pharmacological evaluation of Tilvaka (Viburnum nervosum D. Don): A narrative review.

Divya Jain — 2026-05-24

Introduction

Tilvaka (Viburnum nervosum D. Don.) belongs to the family Caprifoliaceae. It is a deciduous shrub of Himalayan and north-eastern regions of India. In classical texts, it is mentioned under Shyamadi Gana and shat sodhana vriksha (purifying trees), indicating its purgative property. It is an ingredient of formulations like Arguvadi taila, primarily indicated for vata vyadhi (Diseases due to vata imbalance), pandu roga (anaemia)and udara roga (abdominal diseases), etc. The current review compiled the data on Tilvaka and evaluated its traditional claims in light of modern findings.

Methodology

Data were collected and compiled from classical Ayurvedic texts, scientific literature, ethnobotanical data, and pharmacological reports from databases, including PubMed and Web of Science. Information on identification, traditional uses, phytoconstituents, and therapeutic intervention was analysed.

Result

Tilvaka is a medicinal shrub of the Himalayan region of India. It is also known by other names like Telam, Thelka and Asara. It has purgative action. In classical and folk medicine, different parts- bark, fruit, and the whole plant are used to treat various conditions like anaemia and dysmenorrhea, etc. Phytochemical studies have confirmed its antioxidant, antimicrobial, and anti-cancerous activity due to the presence of compounds- terpenoids, triterpenoids and bergenin.

Discussion

Tilvaka is a Himalayan medicinal plant that was confused with Lodhra, later identified as Viburnum nervosum by Thakur Balwant Singh. It is a mild virechaka (purgative) drug with ovate leaves and drupe fruit. In folklore, its fruit, root, and bark are used in anaemia and GIT disorders and is key ingredients of formulations like Tilvaka ghrta and Pippalayadi kshara. Phytochemically, it contains terpenoids, glycosides, etc. responsible for possessing antimicrobial and antioxidant activities.

Conclusion

Tilvaka is classical drug used in conditions like Pandu, Krimi and Kustha. It is an endangered species, requires complete Pharmacognostical-phytochemical profiling along with propagation and conservation techniques for future use.

Narrative Review on Anti-inflammatory Activity of Chloroxylon swietenia DC: Bridging Traditional Claims with Scientific Evidence

Smruti Shahare — 2026-05-24

Background: Chloroxylon swietenia DC (CS) or Bherra (East Indian Satinwood) is a traditional medicinal plant used in the south-eastern part of India. Different parts of this medium -sized deciduous tree, such as leaves, bark and fruits, have been used in folklore medicine to treat pain and inflammatory diseases. In spite of its many ethnomedicinal applications, strong scientific evidences still limited.

Objective: The purpose of this review is to evaluate the anti-inflammatory activity of CS extracts, along with the phytoconstituents involved in this activity.

Materials and Methods: The relevant information was gathered from classical Ayurvedic texts such as Dravyaguna vijnana by P. V. Sharma and standard reference books like Indian Medicinal Plant and Wealth of India. Also, the electronic databases, including PubMed, Science Direct, Google Scholar and IMPPAT 2.0, were searched to compile scientific work related to phytochemical and pharmacological activities.

Results: Phytochemical studies indicate that CS extracts contain a wide range of bioactive compounds, which may be responsible for a dose-dependent anti-inflammatory effect in various experimental models.

Discussion: The anti-inflammatory effect of CS is due to the presence of bioactive components in CS extracts, which can be responsible for modulating key inflammatory pathways, including arachidonic acid through inhibition of lipoxygenase, cyclooxygenase and phospholipase enzymes. Also, it shows a good safety profile with no toxic effects at experimental doses.

Conclusion: Experimental and phytochemical profiles support the traditional claim and scientific validation of anti -inflammatory potential of CS. However, further research on isolation, standardization and multicentric clinical trials is essential to establish a potent anti-inflammatory drug.

Gaming Disorder in the Context of Ayurveda: Bridging Modern Behavioral Addiction with Classical Concepts- A narrative review

Manpreeth Mali Patil — 2026-05-24

Background: Gaming disorder (GD) has become a serious behavioral health issue, particularly among children and adolescents. Excessive electronic gaming activates neural reward pathways, which reinforce behavior through dopaminergic mechanisms similar to substance addiction. The following are signs of video game addiction: fatigue, eye strain, repetitive strain injuries such carpal tunnel syndrome, migraines from extended computer time, and neglect of personal hygiene. Objectives: To conceptualize Gaming Disorder within the framework of Ayurvedic Manasika Vikara, analyze its Nidana and Samprapti, and frame a suitable management through Ayurveda based on the severity of addiction. Methods: A narrative literature review was conducted through systematic examination of classical Ayurvedic Samhita, along with a comprehensive literature review was done through open access, full text publications in English on Gaming disorders. Database searched were PubMed, Science Direct and relevant sources were identified using predefined keywords like Internet Gaming disorders, Gaming disorders in Ayurveda and causes of gaming disorders. The results were correlated with current neurobehavioral knowledge and interpreted using Ayurvedic principles. Results: Gaming Disorder can be correlated with Prajnaparadha, characterized by impairment of Dhee (intellect), Dhriti (self-control), and Smriti (memory). One of the main etiological factors linked to behavioral dysregulation is Asatmendriyartha Samyoga, or improper engagement of sense organs. The predominance of Rajas and Tamas Guna is reflected in the condition, which causes compulsive gaming behavior and poor decision-making. Ayurvedic management, including Satvavajaya Chikitsa, regulation of sensory inputs, and enhancement of Satva Guna, is indicated for restoring psychological balance. Conclusion:
Both contemporary neurobiological and Ayurvedic perspectives are useful in understanding the multifactorial nature of gaming disorder. The development of a stage-by-stage, customized Ayurvedic management protocol to address cognitive and behavioral imbalances is made possible by an understanding of its etiopathogenesis. Particularly for younger populations, these integrative approaches may offer successful management and prevention strategies.

Analytical Review of Ravigupta’s Siddhasara Nighantu

Jayesh Thakkar — 2026-05-24

Background: Siddhasara Samhita and its Siddhasara Nighantu are important text of Indian Medical Science belonging to early medieval period. These were written after the prime three texts - Brihat trayi and before the lesser three texts - Laghu trayi, thus making them important to be referred. Written by Acharya Ravigupta in easy language aim for mediocre this have been a physician guide book. With regard to Nighantu, Siddhasara Nighantu is a pioneer work in Medieval period after Vedic period Nighantus, it has given synonyms of important plants-metal-minerals within less than hundred verses. Objective: To study and analyse importance of Siddhasara Nighantu. Method: Applicable materials are taken from the published texts and available translation by different authors on Siddhasara Samhita and Nighantu - lexicon. Through literature review, the objective of this study is to analyse and highlight the importance and utility of Siddhasara Nighantu. Result: Many interesting findings were found and are discussed. From intellectual historical significance to easy reference, this linguistic archive, an early pharmacopoeia and handy work on many names of important drugs is important As quoted and explored, this is for easy identification of drugs and quick guidance to physician. Conclusion: This work as an essential text to a physician, should be explored to larger extent; as true to Siddhasara Nighantu another name, its Sarottam, best of all. Further studies to see the order and its contribution to other Nighantus, would be helpful to scholars of Dravyaguna and all.