SINGLE- BLIND PLACEBO CONTROLLED CLINICAL EVALUATION OF MAMAJJAKA GHANVATI IN PRAMEHA W.S.R. DIABETES MELLITUS

Abstract

Background:

Prameha (~Diabetes Mellitus) is described as one of the disease mainly caused by vitiation of tridosha. Prameha is one of the eight diseases which are tough to cure known as mahagada (merely curable disease) are numerated by Sushruta.  The syndrome diabetes mellitus has been largely covered under the broad heading of prameha. According to the International Diabetes Federation (IDF), 3.8 million people worldwide die from diabetes and related illnesses annually. In only 20 years the number of people with diabetes has exploded from 30 million to 246 million. By 2025 there will be approximately 380 million people living with diabetes, with the highest increases in new cases occurring in the most diabetics at 40.9 million followed by China with 39.8 millions.

Objective:

To find out an effective and cheap remedy to combat against prameha (~Diabetes Mellitus).

Methods and Materials:

The study was carried out in the 60 patients of prameha selected from the O.P.D/I.P.D of govt. Ayurvedic College hospital Raipur; total of 52 patients completed the full course of treatment. Out of this figure, 20 patients were studied in shamana Group who were given mamajjaka ghanavati, second group with virechana karma fallowed by mamajjaka ghanavati and rest 20 patients Were studied in control group who were given godanti bhasma as placebo treatment.

Results:

The trial drug & virechana (bio-purification) therapy shows highly significant result on objective parameter like reduction in Fasting Blood Sugar level, reduction in Post Prandial Blood Sugar level, along with clinical improvements on subjective parameters like excessive urination, turbidity of urine, excessive thirst, burning sensation in hand and leg, excessive sweating, ,excessive hunger & tiredness etc.

Conclusion:

The drug under trial, mamajjaka ghanavati was effective in Diabetes Mellitus conditions.