Efficacy of internal administration of Tilakanda Kshara in the management of benign prostatic hyperplasia- A pre-post study

Abstract

Background: Benign Prostatic Hyperplasia (BPH) is a prevalent, non-cancerous tumour affecting aging men, significantly contributing to lower urinary tract symptoms (LUTS) worldwide. This condition substantially impacts quality of life. Prevalence of histologic BPH with age is approximately 20% (41-50 years), 50% (51-60 years), and over 90% (above 80 years). Treatment modalities span from conservative management (watchful waiting) to Medical therapy and Surgical intervention. According to Ayurvedic texts, Mutra rogas' severity manifests as vibhanda (obstruction), predominantly observed in Mutraghata. While no single disease mirrors Benign Prostatic Hyperplasia (BPH) exactly, Mutragranthi, described under Mutraghata, shares striking similarities. Objectives: To evaluate the efficacy of internal administration of tilakanda kshara in the management of Benign Prostatic Hyperplasia. Materials and methods: This is a single group pre- post interventional study conducted on 20 participants from OPD and IPD department of salya tantra, Govt Ayurveda College, Thiruvananthapuram. Participants diagnosed with BPH was subjected to internal administration of kshara for a period of 30 days. Conclusion: A majority of the participants experienced significant relief from symptoms of BPH, even though there was no statistically significant reduction in prostate size. Furthermore, the post-void residual urine volume showed a significant reduction in most participants, both clinically and statistically. Therefore, it can be concluded that the internal administration of Tila Kanda Kshara with Dadhi Mastu is both clinically and statistically effective and can be considered a viable approach for the management of BPH.