Ayurvedic management of coexisting hypothyroidism and PCOS: A case report
DOI:
https://doi.org/10.70066/jahm.v13i6.1688Keywords:
Ayurveda, Hypothyroidism, Polycystic Ovarian Syndrome (PCOS), Case ReportAbstract
Background: Hypothyroidism and Polycystic Ovarian Syndrome (PCOS) are common endocrine disorders that frequently coexist, impacting metabolic, hormonal, and reproductive health. This case report explores the potential of Ayurvedic management in addressing these complex conditions. Clinical Presentation: A 17-year-old female presented with symptoms of hypothyroidism, including fatigue, weight gain, hair fall, and irregular menstrual cycles. Diagnostic findings revealed elevated thyroid-stimulating hormone (TSH) levels (39.4 µIU/mL) and features consistent with PCOS. Outcome: The patient received Ayurvedic treatment such as Agnitundi Vati, Kanchanara Guggulu, and Kumaryasava, along with dietary modifications. After six months of treatment, the patient showed marked clinical improvement, including regularization of menstrual cycles, significant weight reduction, and normalization of TSH levels (6.46 µIU/mL after three months, sustained at 5.86 µIU/mL after two years). Ultrasonography confirmed the resolution of PCOS features. No adverse reactions were reported. Patient tolerated the treatment well. Conclusion: The treatment for a period of 6 months has given a good outcome with no adverse events highlighting the potential of Ayurvedic interventions in the holistic management of complex endocrine disorders like hypothyroidism and PCOS. However, further research in this area is necessary to validate the results.
References
Chaker L, Bianco AC, Jonklaas J, Peeters RP. Hypothyroidism. Lancet. 2017 Sep 23;390(10101):1550-1562. 10.1016/S0140-6736(17)30703-1
Taylor PN, Albrecht D, Scholz A, Gutierrez-Buey G, Lazarus JH, Dayan CM; European Thyroid Association. Global epidemiology of hyperthyroidism and hypothyroidism. Nat Rev Endocrinol. 2018 May;14(5):301-316. 10.1038/nrendo.2018.18
Unnikrishnan AG, Menon UV. Thyroid disorders in India: An epidemiological perspective. Indian J Endocrinol Metab. 2011 Jul;15(Suppl 2):S78-81. 10.4103/2230-8210.83329
4.Singla, Rajiv; Gupta, Yashdeep1; Khemani, Manju2; Aggarwal, Sameer3. Thyroid disorders and polycystic ovary syndrome: An emerging relationship. Indian Journal of Endocrinology and Metabolism 19(1):p 25-29, Jan–Feb 2015. 10.4103/2230-8210.146860
Lavanya K, Silambanan S, Ganesh M. Association of hypothyroidism and polycystic ovary syndrome (PCOS). Int J Clin Biochem Res 2019;6(3):405-409. https://doi.org/10.18231/j.ijcbr.2019.087
Nautiyal H, Imam SS, Alshehri S, Ghoneim MM, Afzal M, Alzarea SI, Güven E, Al-Abbasi FA, Kazmi I. Polycystic Ovarian Syndrome: A Complex Disease with a Genetics Approach. Biomedicines. 2022 Feb 24;10(3):540. 10.3390/biomedicines10030540
Kashyapa Samhita, Vridda Jeevaka Tantra of Pandit Hemaraja Sara, revised by Vatsya. Kalpasthana. Visheshakalpa adhyaya. chapter 6, verse no.33. reprint edition. Varanasi: Choukhamba Sanskrita Sansthan; 1953:154
Patel MG, Prajapati DP. Concept of polycystic ovarian syndrome: perspectives of ayurveda and modern science. Int J Pharmacogn Phytochem Res. 2017;9(10):1363-72. https://doi.org/10.25258/phyto.v9i10.10462
Kadam R, Shinde K, Kadam R, MrudulaKulkarni DD. Contemporary and traditional Perspectives of Polycystic Ovarian Syndrome (PCOS): A critical review. IOSR J Dent Med Sci. 2014;13(9):89-98. 10.9790/0853-13968998
Chandra S, Gurao R, Dadhich OP. Conceptual Study Of Hypothyroidism And Agnimandya. International General of Ayurvedic and Herbal medicine. 2015;4:1932-1. http://www.interscience.org.uk/
Shahina Mole.S, & Ammu.K.Sasi. (2021). A Case Study on Ayurvedic Management in PCOS. International Journal of Ayurveda and Pharma Research, 9(11), 80-82. https://doi.org/10.47070/ijapr.v9i11.2111
M, G. S. (2020). Clinical Evaluation of Agnitundi Vati in the management of Gridhrasi With special reference to Sciatica. International Journal of Ayurvedic Medicine, 11(1), 76–80.
Kaur Jagmeet, Chauhan Milan. Kanchnar Guggulu and Varunadi Kashaya in Hypothyroidism- A Case Study. Int. J. Ayur. Pharma Research2014;2(2):58-60. https://doi.org/10.47552/ijam.v11i1.1368
Akanksha Mishra, Lowkesh Chandravanshi, Lalit Mohan Bhatt. Efficacy of Ayurveda Polyherbal Medicine in Polycystic Ovarian Syndrome. InternationalJournal of Ayurveda and Pharma Research. 2023;11(9):66-70. https://doi.org/10.47070/ijapr.v11i9.2966
Aina DA. Establishing the Hormonal Relationship between Polycystic Ovary Syndrome and Hypothyroidism: A Literature Review. Medical Student Research Journal. 2020; 07:001-007. http://msrj.chm.msu.edu/wp-content/uploads/2020/08/MSRJ2019187.pdf
Sinha U, Sinharay K, Saha S, Longkumer TA, Baul SN, Pal SK. Thyroid disorders in polycystic ovarian syndrome subjects: A tertiary hospital based cross-sectional study from Eastern India. Indian journal of endocrinology and metabolism. 2013 Mar 1;17(2):304-9. 10.4103/2230-8210.109714
Lal, *Pravesh T., Lal, S. K., & Garg, S. (2017). A clinical comparative evaluation of efficacy and safety of kumaryasava and rajahpravartani vati in the management of Prathmik Kastartava w.s.r. to (Primary Dysmenorrhoea): A Prospective Open Label Single Center Study. International Journal of Ayurveda and Pharma Research, 5(11). https://ijapr.in/index.php/ijapr/article/view/806
S, Nimmy & Sheba, M. (2021). Exploring the Pharmaco-Therapeutic Efficacy Of Kumari (Aloe Vera L.) on the Reproductive System. World Journal of Pharmaceutical Research. 2021; 10(4).: 1593-1602. 10.20959/wjpr20214-20189
Nampoothiri, Laxmipriya & Maharjan, Radha & Dey, Arpi. (2015). Implication of non polar phytocomponents of aloe vera gel in management of polycystic ovarian syndrome. Endocrine Abstracts. 2015;37. 10.1530/endoabs.37.EP140
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