Pharmacognostic and Pharmaceutical Study of Panchashrisha Agada: A Novel Ayurveda Formulation
DOI:
https://doi.org/10.70066/jahm.v13i9.2013Keywords:
Keywords–AgadaTantra, Panchashirisha Agada Vati, Vicharchika, Pharmacognostical, Pharmaceutical ,HPTLCAbstract
Introduction: In today's era, assessing the quality of herbal formulations is crucial and rationale for confirming authenticity before its market release. The World Health Organization has established guidelines for evaluating the safety, efficacy, and quality of herbal medicines. Panchashirisha Agada is a herbal formulation which comprises of Shirisha Phala, Shirisha Moola, Shirisha Twak, Shirisha Pushpa, Shirisha Patra (Albizzia lebbeck Benth.)Aim: To prepare Panchashirisha Agada Vati and authenticate by carrying out physico-chemical assessment. Materials and Methods: Pharamacognostical evaluation was carried out at Pharmacognosy department and Pharmaceutical study was completed in the Pharmaceutical chemistry department of ITRA, Jamnagar respectively. Results: Pharmacognostical findings confirmed the authenticity and genuine ingredients of Panchashirisha Agada. The average values of physicochemical parameters of Panchashirisha Agada Vati were found as follows: pH value:8, loss on drying:12.8%, total ash value:30%, water soluble extractive value:11.4%, alcohol soluble extractive value:15.9%. The hardness of the Vati 5.02 kg/Cm2. Qualitatively TLC study showed 7 major spots at 256 nm,13 spots at 366 nm. Further HPTLC study showed 6 major spots at 254 nm, 7 spots at 366 nm, 12 spots at 540 nm. Conclusion: The trial drug is genuine and devoid of any adulteration and substitution. Data generated can be used to develop a preliminary standard profile criterion for the formulation Panchashirisha Agada Vati.
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