Efficacy of Ashwagandhadi Leha Granules in comparison to Hyderabad mix on Karshya, undernutrition IAP grade I and II in children – a double blind randomized controlled clinical trial
DOI:
https://doi.org/10.70066/jahm.v13i5.2052Keywords:
Karshya, Undernutrition, Apatarpanajanya Vyadhi, Ashwagandhadi leha granules.Abstract
INTRODUCTION: Apatarpanajanya vyadhi with krushata (wasting) as a cardinal feature is a Karshya and is correlated with undernutrition. Underweight prevalence has decreased from 35.8% to 32.1% (NFHS 5 report). Despite various programmes like Akshaya patra, Rashtriya Bala Swasthya Karyakram to curb under nutrition, the results not satisfactory. Thus, WHO and GOI prioritize malnutrition research with emphasis on traditional food recipes. Researches on formulations like Drakshadi Gritha, Ashwagandha Granules and Prinan Modaka, Balya Biscuit and Kooshmanda avaleha mostly exploratory with few being controlled clinical trials. Studies using z scores assessment on WHO growth charts. Ashwagandhadi leha mentioned in Sahasrayogam – Lehya Prakarana indicated in Karshya possesses Balya property. Difficulty with administration of ghrita, leha yoga were due to the texture, smell or taste of. Thus, a pharmaceutically modified Ashwagandhadi leha granules was proposed for research. This is expected to be wholesome combination by virtue of its ingredients that cover the calorie, proteins, fat and calcium needs of the child along with pepper to enhance bio availability and immunity. Thus, the present study intends to evaluate the effect of Ashwagandhadi leha granules on Karshya, undernutrition IAP grade I and II. MATERIALS AND METHODS: This is a prospective, close-label, double blind randomized controlled clinical trial of total 40 participants diagnosed with Karshya, Undernutrition IAP grade I and II. Trial group subjects will receive for age group 2 to 4 years it will be 15g and for age group 5 to 6 years it will be 20g of Ashwagandhadi leha granules with 100ml milk BD orally, after food for 90 days. Control Group subjects will receive Hyderabad Mix in the similar way. DISCUSSION: The study is expected to show that the intervention of Ashwagandhadi leha granules is as effective as Hyderabad Mix in managing Karshya, Undernutrition IAP grade I and II.
References
Yadav AK, Singhal HK and Vyas PP. A Critical Appraisal of Malnutrition in Ayurveda. J Fam Med. 2021; 8(8): 1276.
Tikole RV, Kulkarni R, Shailaja U, Nithin SA, Mallannavar V, Nayankumar S, Tikole YV. Nutritional deficiency disorders in paediatrics: An Ayurvedic perspective. Int J Res Ayurveda Pharm. 2013;4(4):605–607. Available from http://dx.doi.org/10.7897/2277-4343.04431 (accessed on 6th June 2025)
Paul V K, Bagga A. Ghai Essential Pediatrics. 8thed. New Delhi: CBS Publishers & Distributors Pvt. Ltd; 2013. p.95.
Ministry of Women and Child Development; Measures to Address Malnutrition: 05 AUG: PIB Delhi; 2022.
Chittapur D, Patil SS, Lakshmanappa S. Nutritional status assessment of 6-59 months age children in rural Yadgir, Karnataka state, India. International Journal of Community Medicine and Public Health. 2024;11(4):1585. Available from https://doi.org/10.1007/s41745-025-00470-y (accessed on 6 June 2025)
Gragnolati M, Shekar M, Das Gupta M, Bredenkamp C, Lee YK. India's undernourished children: a call for reform and action. World Bank; 2005:7. Available from https://documents.worldbank.org/en/publication/documents-reports/documentdetail/552991468042034521/indias-undernourished-children-a-call-for-reform-and-action (accessed on 6th June 2025)
Kulkarni R. An integrated approach on child nutrition. J Ayurveda Holist Med. 2013;1(2):8–14. available from https://doi.org/10.70066/jahm.v1i2.423 (accessed on 6th June 2025)
M Manjusha. Effect of Drakshadi Gritha in growth and development of undernourished children aged 2- 5years. (MD Dissertation). Government Ayurveda College. Thiruvananthapuram. Thrissur: Kerala university of health sciences; 2017.
Patil AR, Kulkarni R, Shailaja U, Nithin SA, Swami V. Effect of ashwagandhaghrita on karshya (underweight): an explorative study. Int J Res Ayurveda Pharm. 2016 Mar-Apr;7(Suppl 2):156–159. Available from http://dx.doi.org/10.7897/2277-4343.07278 (accessed on 6th June 2025)
Sivaraj S. An Open label, two arm, Randomized, Active Controlled Clinical trial on the Efficacy of Amritapraasha Ghrita in Children with Karshya (Grade I and II Under Nutrition). (MD Dissertation). Bengaluru: Rajiv Gandhi University of Health Sciences, Karnataka; 2018.
G Jaidev. Efficacy of Paushtika Biscuit with and without Deepana Pachana in The Management of Karshya (Malnutrition) - An Open Labelled, Randomized, Comparative Clinical Trial. (MD Dissertation). Institute For Post Graduate Teaching & Research in Ayurveda. Jamnagar: Gujarat Ayurved University: 2018.
Chavada M G. A Controlled Comparative Study on Ashwagandha Granules and Prinan Modaka in The Management of Karshya (Underweight). (MD Dissertation). Parul Institute of Ayurved, Vadodara. Parul University, Gujarat: 2017.
Lad S R. A Clinical Study on Effect of Balya Biscuit and Prinana Modaka On Krisha Children. (MD Dissertation). Institute for Post Graduate Teaching and Research in Ayurveda, Jamnagar. Gujarat Ayurved University: 2015
Doshi N. A Clinical Study on Brumhana Effect of Prinan Modak and Godhumadi Modak in The Management of Karshya in Children. (MD Dissertation). Institute Of Post Graduate Teaching And research in Ayurveda, Jamnagar. Gujarat Ayurved University: 2011
Jatav G. Comparative Study on The Effect of Vidarikandadi Vati and Kshirabala Taila Basti in The Management of Karshya in Children. (MD Dissertation). Institute of Post Graduate Teaching & Research in Ayurveda Jamnagar. Gujarat Ayurved University: 2008
Effect of Chukkiliratyadi Churna on selected hematological parameters in Undernourished Children of age group 3-6years. (MD Dissertation). Government Ayurveda College, Thiruvananthapuram. Kerala university of health sciences, Thrissur: 2019
Paul Eldho Effect of Ashtamangala Gritha in Undernutrition in children. (MD Dissertation). Government Ayurveda College, Thiruvananthapuram. Kerala university of health sciences, Thrissur: 2016
Arti D K. Assessment of Kushmanda kalpa as dietary Supplement in Malnourished children. (MD Dissertation). PDEA'S College of Ayurved and Research Center Akurdi, Pune. Maharshtra University of Health Science: Nashik; 2021.
Niteshwar K, Vidyanath R, (1st ed. reprint). Sahastrayogam, Lehya prakarana: Chapter 10. Varanasi: Chowkhamba Sanskrit series office; 2017; 261.
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