NEW WORLD SYNDROME (OBESITY) GONE BY GUGGUL: A REVIEW
DOI:
https://doi.org/10.70066/jahm.v2i9.222Keywords:
Obesity, Guggulu, Hyperlipidemic, Anti oxidantAbstract
Background: Obesity is multi factorial disease would lead to excessive or abnormal fat accumulation. Its prevalence is on
continuous rise in all age groups of the developed as well as developing countries in the world and it can be described as
the "New World syndrome". Among the materia medica of Ayurveda, Guggul is essential herb indicated for the
management of obesity but their mechanism of action in relation to scientific parameter is lacking. Aim & Objective: To
review effect of Guggul on New World Syndrome. Materials & Methods: References of Guggul are search out in classical
as well as contemporary science in new world syndrome. Observation: During survey of Ayurvedic literature it was
observed that different herbs, metals, minerals are used for treatment of obesity as single drug as well as in compound
formulations. Among herbs Guggul occupied significant position and effectively used for treatment of obesity. It is oleo
gum resin, obtained from Commiphora mukul originate in India, Bangladesh and Pakistan having anti hyperlipidemic, anti
oxidant, anti inflammatory property which are important pharamcotherapeutic targets in the treatment of obesity agent
of obesity. Besides this Guggul also act as drug delivery medium and help in transportation of anti obesity agent to target
site and performing their action when used with other anti obesity drugs. Conclusion: Guggul is right choice in
management of New World syndrome and probably acting by different pharmacological properties.
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