STABILITY STUDY OF MUSTADI GHANA VATI WITH RESPECT TO VARIOUS MICROBIAL DIAGNOSTIC MODALITIES

Authors

  • Dr. Dipashree Institute of Teaching and Research in Ayurveda.
  • Meera Cholera Institute of Teaching and Research in Ayurveda
  • Dr. Sagar Bhinde ITRA
  • Director, ITRA Institute of Teaching and Research in Ayurveda

DOI:

https://doi.org/10.70066/jahm.v10i4.537

Keywords:

Mustadi Ghana Vati, drug stability, microbial contamination, shelf life

Abstract

Background: In last few decades, market of herbal and traditional medicines have grown up in leaps and bounds, but majority of traditional medicines are lacking in its data of Saviryatavadhi (shelf-life period). Hence the present study was carried out to evaluate the stability of Mustadi Ghana Vati with respect to microbial contamination and fungal growth. Material and method: Mustadi Ghana Vati was prepared in the pharmacy, ITRA and stored in food grade air-tight plastic containers, in a well-ventilated, well lighted space at room temperature. A baseline microbial profile was studied at regular interval of 1 month for total 13 months. Every time, the sample was subjected to microbiological studies like smear examination with wet mount - 10% K.O.H. preparation and Gram’s stain; fungal culture; and aerobic culture at Microbiology Laboratory, ITRA, Jamnagar. Results: In this study, no any growth of micro-organisms (bacterial or fungal) was found till 2nd March 2022 i.e. for 13months from the date of preparation. Conclusion: Hence this study shows that Mustadi Ghana Vati can remain stable in various climatic conditions for a minimum of 13 months and remain free from any microbial contamination, which indicate that the manufacturing and storage practices adopted in this study was up to the mark of Good Manufacturing Practice (GMP) and could be used as quality standards by future researchers and drug manufacturers.

Additional Files

Published

2022-11-19

How to Cite

Gauns, D., Cholera, M. ., Bhinde, S., & Thakar, A. . (2022). STABILITY STUDY OF MUSTADI GHANA VATI WITH RESPECT TO VARIOUS MICROBIAL DIAGNOSTIC MODALITIES. Journal of Ayurveda and Holistic Medicine (JAHM), 10(4). https://doi.org/10.70066/jahm.v10i4.537

Issue

Vol. 10 No. 4 (2022): Journal of Ayurveda and Holistic Medicine (JAHM)

Section

Original Research Article- Experimental Research

License

Copyright (c) 2022 Dr. Dipashree, Meera Cholera, Dr. Sagar Bhinde, Director, ITRA

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Authors retain the copyright of their work and grant the Journal of Ayurveda and Holistic Medicine (JAHM) the right of first publication. All published articles are licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) license, which permits non-commercial sharing, use, distribution, and adaptation with proper attribution and the same license terms.

JAHM ensures free, irrevocable, worldwide access to its content. Users may copy, distribute, display, and share published works for non-commercial purposes with appropriate credit to the author(s) and the journal. Limited printed copies for personal, non-commercial use are allowed under the same license.

If a submission is not accepted for publication, the author(s) will be notified.

By submitting, authors confirm that the work is original, that all listed authors have contributed and approved it, and that it does not infringe any third-party rights or duplicate work submitted elsewhere.