AN EXPERIMENTAL STUDY TO EVALUATE EFFICACY OF DHATAKYADI YOGA LEPA IN BURN WOUND HEALING
DOI:
https://doi.org/10.70066/jahm.v2i4.167Keywords:
Burns, AgnidagdaVrana, Dhatakyadi Yoga, lepa, Silverex, Wound healingAbstract
Background: Burn is coagulative necrosis of the tissues and Scalds are caused by contact of hot liquid
with skin. The incidence in India is six to seven million; nearly 10% of them require hospitalization.
Management of 1st degree and 2nd degree burn involves dressings with antibiotic ointments which
reduce microbial load on the burn surface but potentially prolongs healing time and pain during
repeated dressing. Sushruta mainly emphasizes the importance of lepa in DagdaVrana which reduces
daha, sphota, vedana and does Vranaropana. Dhatakyadi yoga lepa is such preparation which meets all
the above needs and mainly indicated in Agnidagda Vrana. Objective: To evaluate wound healing
property of Dhatakyadi Yoga Lepa in moist heat induced burns in rats. Material and methods: Partial
thickness burns were inflicted on three groups of rats (n=6 in each group) at back under ether
anesthesia. Standard group was treated with Silverex ointment, test group with Dhatakyadi Yoga (DY)
and control group with normal saline twice till complete healing. Study duration was for 21 days and
the parameters observed were epithelialization period, hydroxyproline content, Scar area, wound
contraction rate. Data was analyzed by one way ANOVA method. Results: There was significant
increase in wound contraction rate, Hydroxyproline content and decreased period of Epithelization,
Scar area in the group treated with Dhatakyadi yoga. Conclusion - Dhatakyadi yoga is effective in
healing of burn wound.
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